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Diabetes control and complications trial : ウィキペディア英語版 | Diabetes control and complications trial The Diabetes Control and Complications Trial (DCCT), was a landmark medical study conducted by the United States National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It significantly changed the management principles of Diabetes mellitus from the 1990s onwards. The completed study was published in the ''New England Journal of Medicine'' in 1993. A study in the United Kingdom known as the United Kingdom Prospective Diabetes Study (UKPDS), released in 1999, found similar results for people with type 2 diabetes.〔(Diabetes Trials Unit. Oxford University. United Kingdom Prospective Diabetes Study )〕 Between the two studies, the treatment of people with diabetes was significantly changed. ==Purpose== Long-term microvascular and neurologic complications cause major morbidity and mortality in patients with diabetes, and is the leading cause of blindness in the developed world. This study examined whether intensive treatment with the goal of maintaining blood glucose concentrations close to the normal range could decrease the frequency and severity of those complications.
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